People
Helena L. A. Vieira
Research Lab Leader
Email
hl.vieira@fct.unl.pt
Phone number
-
Researcher ID
ORCID
Ciência Vitae
Recent publications
- Figueiredo-Pereira, C; Dias-Pedroso, D; Soares, NL; Vieira, HLA. 2020. CO-mediated cytoprotection is dependent on cell metabolism modulation. Redox Biology, 32, DOI: 10.1016/j.redox.2020.101470
- Oliveira, Sara R.; Figueiredo-Pereira, Cláudia; Duarte, Carlos B.; Vieira, Helena L.A.. 2019. P2X7 Receptors Mediate CO-Induced Alterations in Gene Expression in Cultured Cortical Astrocytes—Transcriptomic Study. MOLECULAR NEUROBIOLOGY, 56, DOI: 10.1007/s12035-018-1302-7
- Dias-Pedroso, Daniela; Guerra, Joel; Gomes, Andreia; Oudot, Carole; Brenner, Catherine; Santos, Cláudia N.; Vieira, Helena L.A.. 2019. Phenolic Metabolites Modulate Cardiomyocyte Beating in Response to Isoproterenol. Cardiovascular Toxicology, 19, DOI: 10.1007/s12012-018-9485-8
- Oudot, Carole; Gomes, Andreia; Nicolas, Valérie; Le Gall, Morgane; Chaffey, Philippe; Broussard, Cédric; Calamita, Giuseppe; Mastrodonato, Maria; Gena, Patrizia; Perfettini, Jean Luc; Hamelin, Jocelyne; Lemoine, Antoinette; Fischmeister, Rodolphe; Vieira, Helena L.A.; Santos, Claudia N.; Brenner, Catherine. 2019. CSRP3 mediates polyphenols-induced cardioprotection in hypertension. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 66, DOI: 10.1016/j.jnutbio.2019.01.001
- Osório, Daniel Noronha; Viana-Soares, Ricardo; Marto, João Pedro; Mendonça, Marcelo D.; Silva, Hugo P.; Quaresma, Cláudia; Viana-Baptista, Miguel; Gamboa, Hugo; Vieira, Helena L. A.. 2019. Autonomic nervous system response to remote ischemic conditioning: heart rate variability assessment. BMC Cardiovascular Disorders, 19, DOI: 10.1186/s12872-019-1181-5
- Almeida, Ana S.; Soares, Nuno L.; Sequeira, Catarina O.; Pereira, Sofia A.; Sonnewald, Ursula; Vieira, Helena L.A.. 2018. Improvement of neuronal differentiation by carbon monoxide: role of pentose phosphate pathway. Redox Biology, 17, DOI: 10.1016/j.redox.2018.05.004
Main research interests
- Cerebral ischemia and reperfusion events – ischemic stroke and perinatal hypoxic-ischemic encephalopathy
- Molecular mechanisms underlying preconditioning-induced cytoprotection, in particular remote ischemic conditioning
- Carbon monoxide as a gasotransmitter for promoting cytoprotection and homeostasis in Central Nervous System
- Mitostasis – mitochondrial homeostasis – controlled balance between mitochondrial biogenesis, mitochondrial function and mitophagy (elimination of damaged mitochondria)
- Implication of cell metabolism on cell survival and function, namely neuronal function, neuroinflammatory activity of microglia and astrocytic homeostasis
- Crosstalk between apoptosis, autophagy and cell differentiation
Degrees
- PhD in Oncobiology, Université Paris VII and Centre National pour la Recherche Scientifique (CNRS), France (2002)